e3 ligase ligand 8 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17879	E3 ligase Ligand 8		Others , Ligand for E3 Ligase
	E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. The E3 ligase Ligand 8 can be linked to protein ligands through linkers to form PROTACs, which are inducers of ubiquitination-mediated degradation of cancer-promoti...		Others , Ligand for E3 Ligase
T17916	Pomalidomide-PEG4-C2-NH2	Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22	Others , Ligand for E3 Ligase
	Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.		Others , Ligand for E3 Ligase
T17909	(S,R,S)-AHPC-PEG3-N3	VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12	Others , E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase
	(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC tec...
T17900	CIAP1 Ligand-Linker Conjugates 8	E3 ligase Ligand-Linker Conjugates 46	Others
	cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].		Others
T17819	Thalidomide-O-amido-C8-NH2	E3 Ligase Ligand-Linker Conjugates 20,Cereblon Ligand-Linker Conjugates 2	Others
	Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of...		Others
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl	VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8	Others
	(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in ce...		Others
T17882	Pomalidomide-PEG3-C2-NH2 (TFA)	Cereblon Ligand-Linker Conjugates 5 (TFA),E3 ligase Ligand-Linker Conjugates 30 (TFA),Pomalidomide-PEG3-C2-NH2 (TFA) (2093416-31-8 free base)	Others
	Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.		Others
T40148	Pom-8PEG
	Pom-8PEG is an E3 ubiquitin ligase ligand-linker conjugate consisting of a cereblon (CRBN) ligand and an 8-unit PEG linker. This compound can be utilized for the synthesis of PROTAC, including the IDO1 PROTAC degrader.
T40149	Thalidomide-NH-PEG8-Ts	Thalidomide-NH-PEG8-Ts
	Thalidomide-NH-PEG8-Ts is a chemically synthesized conjugate consisting of a Thalidomide-based cereblon ligand and an 8-unit PEG linker. This conjugate serves as an E3 ligase ligand-linker in PROTAC technology applicatio...
T13958	VHL Ligand 8		Others
	VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. It efficiently facilitates the degradation of AR protein in AR-positive p...		Others
T36800	EN219
	EN219 is a synthetic recruiter of the E3 ubiquitin ligase RNF114.1It binds to cysteine 8 (C8) in the intrinsically disordered region of RNF114 (RNF114-C8; IC50= 470 nM) and inhibits RNF114-induced autoubiquitination and ...